Latest REAL WORLD data on vaccine EFFECTIVENESS
Latest REAL WORLD data on vaccine EFFECTIVENESS (versus efficacy which is from clinical trials) shows that Pfizer, Sinovac and Astra are ALL EQUALLY effective in preventing symptomatic and severe disease.
Pfizer effectiveness data: Up to 90 to 95% effectiveness in preventing symptomatic disease in real world studies from Israel and the USA. Up to 100% effective in preventing death.
Astra effectiveness data: Up to 90% effectiveness in preventing symptomatic disease in real world studies from UK. Up to 100% effective in preventing death.
Sinovac effectiveness data: Up to 94% effectiveness in preventing symptomatic disease in real world studies from Chile and Indonesia. Up to 100% effective in preventing death.
Of course there are differences. Issues in logistics - Pfizer requires ultra low temperatures, so it is difficult to roll out. The studies on prevention of asymptomatic disease are ongoing but early indications are that most vaccines do prevent at least some asymptomatic disease - this was enough for US CDC to drastically modify mask mandates for the fully vaccinated. Cluster trials to see interruption of community transmission are ongoing, the most advanced of which is Sinovac in Serrana in Brazil - prelim data is encouraging and primary outcome data is due this May.
Vaccines work and they work well. All the vaccines we have currently will significantly prevent symptomatic and severe disease and will interrupt at least some transmission. Protecting the most vulnerable, especially our seniors will allow us to cautiously dial back our restrictions. If we get a substantial number of seniors vaccinated, we can seriously consider letting them out and letting the kids out and start school as well. When Israel was able to vaccinate 50% of their seniors, deaths and cases drasticaly went down. A2 group (seniors) is at less than 10% vaccinated currently and there is substantial hesitancy. Please, please, please help us convince our seniors to get ANY vaccine available NOW. Fully vaccinating this group is the key to everyone's freedom.
Source: Edsel Maurice Salvana
